"Louise of Savoy (11 September 1476 – 22 September 1531) was a French noble and regent, Duchess suo jure of Auvergne and Bourbon, Duchess of Nemours, ...
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and the mother of King Francis I. She was politically active and served as the regent of France in 1515, in 1525–1526 and in 1529." - (en.wikipedia.org 30.01.2020)