"The Fourteen Holy Helpers are a group of saints venerated together in Roman Catholicism because their intercession is believed to be particularly effective, especially against various ...
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diseases. This group of Nothelfer ("helpers in need") originated in the 14th century at first in the Rhineland, largely as a result of the epidemic (probably of bubonic plague) that became known as the Black Death." - (en.wikipedia.org 22.10.2019)